Avacor®, from Global vision 2001, is a heavily marketed product that is a three-fold system of a DHT blocker, topical solution, and scalp detoxifying shampoo. It claims to be an all-natural, herbal formulation that is effective immediately, with results shown in 4-6 months. It is a hair-growth stimulator based on a formulation of minoxidil 2%. It also contains sabal serulate, an androgen modulator, more commonly known as saw palmetto. While the company uses “clinical” daya to support its claims, they are in actuality a “non-peer-reviewed, non-double-blind, seemingly scientific study subsidized by the makers of the product*.” The average cost is $220 for a three month supply.
Nioxin® is a cleanser scalp therapy and scalp serum. The product contains niocidin, which inhibits demodex produced lipase. However, according Dr. Ken Washenik “there has never been any study, that I am aware, that implicates demodex lipase in hair loss” or “that shows that hair will benefit from getting rid of mites or their lipase.” Nioxin is based on bionutrient actives and protectives. Their primary methodology is to clean the scalp of DHT and to provide chemically enhanced hair with moisture/vitamin nourishment. Primarily available in salons, the product can now be found in other retail outlets.
Dutasteride, from Glaxo Smith Kline, is the most promising of the products or medications outside of Rogaine and Finesturide. Approved by the FDA only for use with prostate therapy, it was not submitted for male pattern baldness. It is a DHT blocker that blocks both forms of 2-alpha reductase enzymes (type 1and 2). Early studies show promising results, that is , slightly better than finasteride; however, the potential side effects require further trials and testing for overall efficacy and safety. Other early indications show that it has a longer half-life than finasteride and that the safety data is consistent with DHT reduction. It is still awaiting phase III trials. Dutasteride has been marketed with the brand name Avodart®
Saw palmetto is available from multiple sources. It is an over-the-counter herb that has been claimed as effective as a supplement for thinning hair. It has been shown to be beneficial in men with benign prostatic hyperplasia, but does not affect testosterone, DHT, or PSA levels. General usage recommends taking 400mgof standardized extract with 100 mg of beta sitosterol, daily. It is claimed that results will appear in five months.
* * This information was taken from The Hair Transplant Forum International, May/June 2003, pg229-331
* Altcheck, Douglas, MD, Mt. Sinai School of Medicine, in Men’s Health magazine, September 2002.
Lotions, Potions, and Shampoos
Herbals, minoxidel-based, oils, and vitamins
Folliguard Extra, from Jungle MD, is very similar to Avacor both in terms of usage and formulation. Specifically, it uses a system of DHT blocker and scalp detoxifying shampoo. Its active ingredients are minoxidil 2% and saw palmetto. It costs approximately $200 for a 3 month supply.
Hair Advantage, from Daniel Rogers Laboratory, is extremely similar to both Avacor and Folliguard. It uses a DHT blocker, nutrient serum, and scalp detoxifying shampoo. Its ingredients are composed of loniten (better identified as minoxidil), saw palmetto, tarakaci, notoptcryl, maidenhair tree, vaccinium murtillus, and euisetum. The estimated cost is $180 for a 3 month supply.
Xandrox also claims to contain a DHT blocker as well as a topical solution. Its active ingredients are minoxidil (12.5% micronized), azeliec acid 5%, and betamethasone valerate. The company reports that the 12.5% micronized minoxidil works on the temple and hairlines (non-responsive areas), while they say the azeleic acid can act as a DHT inhibitor .
Hair Genesis, from Sunset Marketing, sells for $270 for a 3 month supply. It uses a system of a special shampoo, conditioner, supplements, and a serum. It also uses “botanicals” to inhibit type I and II 5-alpha reductase and decrease DHT. Results are claimed to appear in 6 months and it is described as being safe for both men and women. Hair Genesis is comprisedof Saw Pametto and Beta Sestoserone. The women’s serum is 2% minoxidil with Beta Sestosterone, while the men’s formula is 5% minoxidil with Beta Sestosterone. The studies that claim to render this product effective have been questioned by the medical profession for legitimacy.
Nu Hair™, from Bioteck Corp., sells for $180 for a 3-month supply. It claims to be a “supplement” for thinning hair. Its active ingredients are he shou wou, saw palmetto, horsetail, henna, rosemary, progesterone, and nettle.
Hair Prime™, from Universal Biologics, sells for $210 for a 3 month supply. It requires a regimen of shampoo, lotion, and primer to deliver “nutrients,” It has two herbal and vitamin supplement tablets containing pantothenic acid, biotin, and zinc. It claims to be a natural herbal treatment and that 9 out of 10 have healthier hair growth.
Emu oil, studied by Boston University Medical Center, is a topic product that sells for $9.50 an ounce. Its “credentials” cite a Dr. Michael Holick, who reported a clinical study showing that Emu Oil accelerated skin regeneration and stimulated hair growth. They claim that 80% of hair follicles began to grow hair in non-clinical studies.
Thymuskin, from Bioteckne Complex Inc., sells for $210 for a 3 month supply. It is a topical solution that must be massaged directly into the scalp. It contains the extract of calf thymus glands and claims to boost immune function. The company admits it is not effective for male pattern baldness or androgenetic alopecia, the most common types of hair loss.
FNS, Follicle Nutrient Serum, from Osmotics, sells for $65 for a 4-ounce tube. It is a topical solution that claims to contain a unique delivery system of nutrients. It is marketed as a cosmetic product and will not be submitted for FDA approval. No trials have been performed to date .
Vitamin and Mineral Products
Hair-ZX™, from Bitafree, sells for $250 for a 3-month supply. It is a three-part system including a shampoo, a topical, and a DHT blocker. It is available through the Internet and direct sales. It claims to regrow lost hair as well as to produce larger, healthier follicles.
Folligen™ is available in three formulations: a cream for hairlines, a lotion for denser areas of hair, and a solution therapy spray for misting over the hair. It is available through the Internet and direct sales. It is a copper peptide-based product. Its functionality is based on the theory of increasing blood supply to the scalp to combat hair loss.
Triaxon™ is a topical treatment. It is available through the Internet and direct sales. It is comprised of a combination of vital nutrients and vitamins and reports it has a higher level of active ingredients designed to promote new growth. It claims to help reduce DHT levels by 90% and to give users immediate results.
EPM, from Sumitomo Electronics, is an over-the-counter topical treatment comprised of 10 amino acids. Its active ingredient is epimorphin. No clinical trial data is available and it is not available in the United States .
Kevis®, by Farmaka, sells for $650-$975, depending on the package you choose. It is available through the Internet and direct sales. It includes a topical “accelerator” that must be applied with applicator and massaged. It claims to block DHT or the androgen receptor. The company indicates clinical testing done in Europe.
Procyanidin B-2 is a combination shampoo, lotion, and primer as a regimen to deliver nutrients. It is a polyphenyl compound, found in apples, which is said to act on hair epithelial cells as a growth-promoting factor. Their own study indicated “an increase in the number of hairs and the diameter of hairs in the designated scalp area compared to placebo.” No statistics or data were provided.
Revivogen™, from Advanced Skin and Hair, costs $99 for a 3-month supply. It is available over-the-counter and includes a scalp therapy formula and bio-cleansing shampoo. It says it is an anti-DHT product, and claims there are no systemic side effects and is safe for men and women. It does not have FDA approval. On their own Website, it states that it is “not a drug, medication, treatment, or cure for hair loss.” It also claims internal studies performed showed significant decrease in hair loss in 3 months .
Nizoral®, by Janssen Pharmaceuticals, is a shampoo containing ketoconazole 2% (an anti-fungal agent). Ketoconazole, taken in tablet form, has been shown to lower serum testoterone. The effect has been compared to that of monoxidil 2%. It is available in 1% form over-the-counter or in 2% form as a prescription.
Spironolactone is a potassium sparing diuretic, used in treatment for blood pressure, and has been found to have anti-androgen activity. It is a DHT blocker in topical form and must be applied daily followed by the application of a monocidil solution. It is available by prescription in tablet or foam.
Lasercomb, by Lexington International, claims to use photobiostimulation with low-level, cold beam laser therapy. It claims to show improvements or activation of hair in the first 5-10 weeks. It requires usage twice a day for 10 minutes per session. It has had some mixed reactions. Some of the positive responses are from respondents using other forms of hair loss remedies. It has begun FDA clinical trials. It sells for $695.
Hairogenics™ is a hair storage service in a temperature-controlled vault. The principle involves storing hair until cloning or other reproduction methods are viable. Concerns revolve around the extraction of hair and that DNA taken from existing hair would be sufficient for any cloning or reproducing possibilities. Based in Oregon, cost is an initial $50 plus $10 per annum for storage.
Dermal Fusion, By Ryan Livingston, claims to be a hair “multiplication” technique in which microscopic biopsies of hair or scalp tissue are removed without scarring or blood. Follicles are multiplied in a type of incubation chamber and a pipette then inserts surviving cells. The procedure claims immediate hair growth without any trauma or resting phase. It is generally believed to be a hoax .
The above products may be trendy, tested, or FDA approved, but the question that needs to be answered, is, WHAT WILL WORK FOR YOU? Are you a good candidate for any of these products or any of the proven prescription drugs? Will any of these products meet your expectations and give you results that will meet your satisfaction? While no drug or medication is guaranteed to work, it is best to place the odds in your favor. Call us today at 1-800-322-1237, or email us from this site to set up a free, confidential evaluation. We will examine your scalp and ask a series of questions that will help us determine if any of these products are right for you.